
MOTS-c
MOTS-c is a mitochondrial-derived peptide studied for its role in metabolic signaling and cellular stress responses. It’s often referenced in research…
Mechanism of Action
See published literature and COA for batch-specific analytical data. Research use only — not for human or veterinary administration.
Research Applications
- In vitro laboratory research
- Receptor and pathway assays
- Comparative peptide studies
Specifications
| appearance | See COA for lot-specific appearance and identity confirmation |
Reconstitution (Laboratory)
Reconstitute with bacteriostatic water under sterile laboratory conditions unless otherwise specified for your protocol.
Storage & Handling
Lyophilized: 2–8 °C long-term. Reconstituted: refrigerate at 2–8 °C. Protect from light.
Quality Assurance
Every lot undergoes independent third-party HPLC purity analysis, mass spectrometry identity confirmation, and endotoxin testing (<0.5 EU/mg). Certificate of Analysis (COA) is stored against the SKU lot number and available through your research account portal.
Sources & References
- 1.Lee C, et al. The mitochondrial-derived peptide MOTS-c promotes metabolic homeostasis and reduces obesity and insulin resistance. Cell Metab. 2015. · PubMed →
- 2.Kim KH, et al. The Mitochondrial-Encoded Peptide MOTS-c Translocates to the Nucleus to Regulate Nuclear Gene Expression in Response to Metabolic Stress. Cell Metab. 2018. · PubMed →
- 3.Wan W, et al. Mitochondria-derived peptide MOTS-c: effects and mechanisms related to stress, metabolism and aging. J Transl Med. 2023. · PubMed →