GLP-2
GLP-2 is an intestinal growth factor peptide studied for its trophic effects on the GI mucosa, nutrient absorption, and gut barrier function in research models.
Mechanism of Action
GLP-2 acts via the GLP-2 receptor (GLP2R) expressed on intestinal enteroendocrine cells, promoting crypt cell proliferation, reducing apoptosis, and enhancing barrier integrity in preclinical models.
Research Applications
- Intestinal mucosal growth assays
- Gut barrier permeability research
- Short bowel syndrome model studies
- Nutrient absorption pathway research
Specifications
| sequence | GLP-2 analogue |
| molecular Weight | ~3.9 kDa (native GLP-2) |
| appearance | White lyophilized powder |
Reconstitution (Laboratory)
Reconstitute with bacteriostatic water per protocol. Verify mass against COA.
Storage & Handling
Lyophilized: 2–8 °C for extended storage. Reconstituted: refrigerate at 2–8 °C.
Quality Assurance
Every lot undergoes independent third-party HPLC purity analysis, mass spectrometry identity confirmation, and endotoxin testing (<0.5 EU/mg). Certificate of Analysis (COA) is stored against the SKU lot number and available through your research account portal.