CJC-1295 No DAC
CJC-1295 (without DAC) is a tetrasubstituted GHRH analogue that stimulates growth hormone release from the anterior pituitary in research models, with a shorter half-life than the DAC-conjugated form.
Mechanism of Action
Binds GHRH receptors on somatotroph cells, triggering pulsatile GH release. The No-DAC form provides a shorter-acting profile suitable for protocols requiring discrete GH pulses.
Research Applications
- GH pulse dynamics research
- GHRH receptor binding assays
- Pituitary somatotroph function studies
Specifications
| sequence | Modified GHRH(1-29) analogue |
| molecular Weight | ~3367 Da |
| appearance | White lyophilized powder |
Reconstitution (Laboratory)
Reconstitute with bacteriostatic water. GH secretagogues are sensitive — use gentle swirling.
Storage & Handling
Lyophilized: 2–8 °C. Reconstituted: refrigerate; use promptly per protocol.
Quality Assurance
Every lot undergoes independent third-party HPLC purity analysis, mass spectrometry identity confirmation, and endotoxin testing (<0.5 EU/mg). Certificate of Analysis (COA) is stored against the SKU lot number and available through your research account portal.